Matching emerging formic acid synthesis processes with application requirements

Treatment of Warts with Topical Formic Acid

Understanding underlying processes in formic acid fuel cells.

A basic understanding of electrode structure and the characteristics of its components can be powerfully utilized in fuel cell applications such as direct formic acid fuel cell (DFAFC) system integration and HCOOH concentration controlled systems. There have been, thus, tremendous efforts made to elucidate theoretical aspects of electrochemical processes involving new anode catalysts and put th...

Reaction of atomic hydrogen with formic acid.

We study the reaction of atomic hydrogen with formic acid and characterize the radical products using IR spectroscopy in a Kr matrix and quantum chemical calculations. The reaction first leads to the formation of an intermediate radical trans-H2COOH, which converts to the more stable radical trans-cis-HC(OH)2via hydrogen atom tunneling on a timescale of hours at 4.3 K. These open-shell species ...

Acylation of hydrazides with acetic acid and formic acid.

In peptide synthesis, hydrazides are important intermediates for the azide coupling method. A hydrazide is converted to the corresponding azide in the presence of an acid and a nitrite. When acetic acid (or formic acid) is used as the acid, partial acetylation (or formylation) of the hydrazide occurs as a side reaction. Formylation of the hydrazide is much faster than acetylation. Removal of th...

Synthesis of Naphthopyranopyrimidines Using Formic Acid as an Effective Catalyst under Solvent-free Conditions

An environmentally friendly, one-pot, three-component synthesis of 8,10-dimethyl-12-aryl-12H-naphtho[1′,2′:5,6]pyrano[2,3-d]pyrimidine-9,11-diones was achieved via coupling aromatic of aldehydes, β-naphthol and 6-amino-1,3-dimethyl uracil in the presence of formic acid as a catalyst under solvent-free conditions at 90 °C. This method has several advantages, such as efficiency, good yield, short...